From former George W. Bush speechwriter David Frum at The Atlantic:
DeSantis will be a candidate of the Republican base, for the Republican base. Like Trump, he delights in displaying his lack of regard for everyone else. Trump, however, is driven by his psychopathologies and cannot emotionally cope with disagreement. DeSantis is a rational actor and is following what somebody has convinced him is a sound strategy. It looks like this:
1. Woo the Fox audience and win the Republican nomination.
3. Become president.
Written out like that, you can see the missing piece. DeSantis is surely intelligent and disciplined enough to see it too. But the programming installed in him prevents him from acting on what he sees. His approach to winning the nomination will put the general election beyond his grasp. He must hope that some external catastrophe will defeat his Democratic opponent for him—a recession, maybe—because DeSantis is choosing a path that cannot get him to his goal.